Monday, April 4, 2011

The baby who'll bring women fresh hope of becoming a mother at 50


This is the baby who is set to change the future of fertility treatment for British women.
Olivia Bate’s birth will give hope to hundreds of women who need to freeze their eggs for future fertility treatment.
For Olivia is the UK’s first baby to be born from an egg that was flash frozen – frozen in less than 60 seconds. Months later the egg was thawed, fertilised and placed in her mother Karen Bateman’s womb.


Experts say the technique gives women the chance to have a child at 50 with no greater chance of miscarriage or Down’s syndrome than they had at 30.
The chances of a successful pregnancy following thawing from ‘vitrified’ – or flash frozen – eggs increase dramatically, they explained. With normal freezing techniques, which takes about two hours, 65 per cent of eggs survive the thawing process. With vitrification this rises to 95 per cent.


Gillian Lockwood, of Midland Fertility Services, who carried out the treatment, said: ‘Her birth gives hope to the many young women who want to preserve their fertility before they have life-saving cancer treatment – and also to those women who know that they want to be mothers one day, but can’t try for a baby now.
‘Because so many more eggs survive this thawing process, it means that women can have just one cycle of treatment and get enough eggs to freeze, instead of having to have several treatment cycles.
‘It means that many more women will be able to have this opportunity, which will change the course of fertility treatment in the UK and the way that women look at their lives.’


Women in their early 30s currently have a narrow window of opportunity to become pregnant before the quality of their eggs decline.
But Dr Lockwood added: ‘Vitrification will be as influential for women as the contraceptive pill. They will no longer have to worry about the narrow window.
‘If they freeze their eggs at 30, then those eggs will stay that age for ever, so they can have a baby even at 50 with no greater chance of miscarriage or Down’s syndrome than they had at 30.’
Olivia’s parents, Carl Bate and Miss Bateman, who live in Wolverhampton, started trying for a family in 2002. But Karen, 36, a chemist dispenser, had been diagnosed with endometriosis and doctors warned she may not be able to conceive.

But they refused to give up hope and in 2009, the couple began a course of IVF treatment. Karen managed to produce 17 eggs, but only one viable embryo developed and the treatment failed.
Mr Bate, 40, a director of a catering equipment company, said: ‘We were absolutely devastated when the treatment failed. We had been pinning all our hopes on it working.’
In 2009 the couple decided to try again with IVF. They were first to try the freezing technique and eight of Karen’s eggs were ‘flash frozen’.
For the process, the egg is laid on a film-like ‘leaf’ and it is placed within a tiny droplet of solution. It is then passed through liquid nitrogen gases which rapidly freezes the liquid droplet to a glass like solid in which the egg is preserved.
The whole process takes less than a minute and the egg is then immediately stored in liquid nitrogen for future use.

Dr Lockwood said: ‘Because it is frozen so quickly, the egg undergoes less structural damage which means it is has a better chance of surviving the thawing process.’
In March 2010, five months after they were flash frozen, Miss Bateman’s eggs were thawed and two embryos were put back into her womb.
The couple faced a tense two-week wait to find out if the treatment had been successful. Miss Bateman said: ‘It was the longest wait of our lives. I did a pregnancy test early one morning and ran in screaming to Carl that it was positive.We were just overjoyed when she was born.’




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